The Condensation Reaction of Fatty Acid Biosynthesis
نویسندگان
چکیده
منابع مشابه
The condensation reaction of fatty acid biosynthesis. II. Requirement of the enzymes of the condensation reaction for fatty acid synthesis.
A yeast system differs only in that the major product is stearylCo.4 (5, 6) rather than the free fatty acid, palmitate, as in the other systems. The fatty acid synthetase reaction appears to be a multistage reaction catalyzed by a particulate enzyme complex estimated to have a molecular weight of 2,000,OOO in yeast (6) and to be readily sedimentable by ultracentrifugation in adipose tissue (4) ...
متن کاملThe Condensation Reaction of Fatty Acid Biosynthesis II. REQUIREMENT OF THE ENZYMES OF THE CONDENSATION REACTION FOR FATTY ACID SYNTHESIS PETER GOLDMAN, A. W. ALBERTS, AND P. ROY VAGELOS
A yeast system differs only in that the major product is stearylCo.4 (5, 6) rather than the free fatty acid, palmitate, as in the other systems. The fatty acid synthetase reaction appears to be a multistage reaction catalyzed by a particulate enzyme complex estimated to have a molecular weight of 2,000,OOO in yeast (6) and to be readily sedimentable by ultracentrifugation in adipose tissue (4) ...
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acids were detected as primary products of elonRoot surfaces are protected against the soil environment by the deposition of lignin and suberin. In order to obtain more insight into the regulation of root suberin biosynthesis, elongases from primary roots of corn (Zea mays L.) seedlings were characterized. Elongase activities (acyl-CoA and ATP-dependent) were located in the microsomal fraction ...
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Long chain fatty acid biosynthesis proceeds through a condensation between acetyl coenzyme A and malonyl coenzyme A (1,2) as has now been shown in fatty acid synthetase systems from animal (3), plant (4), and microbial (5-7, Sl) sources. With studies on extracts of Escherichia coli, in which the major product is vaccenic acid, Lennarz, Light, and Bloch (7) have shown and we have confirmed (8) t...
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The original observation of Brady and Gurin (1) and Dituri and Gurin (2) that citrate stimulated fatty acid biosynthesis has been confirmed and extended by many other workers (3-8). Brady, Mamoon, and Stadtman (4) showed that the stimulation of fatty acid synthesis by citrate was due in part to the generation of reduced nicotinamide adenine dinucleotide phosphate (NADPH) by cis-aconitase and is...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1963
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)81172-3